Rabbit anti-VASP Antibody
Catalog #
VASP
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 330 and 380
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Dog
Human
2 - 8 °C
1 year from date of receipt
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG [taken from NCBI Entrez Gene (Gene ID: 7408)].
Alternate Names
vasodilator-stimulated phosphoprotein; VASP
Applications