/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-USP48 Antibody
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Primary Antibodies  

Rabbit anti-USP48 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (7)
Target:

USP48

Reactivity:

Human

,

Mouse

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 985 and 1035

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Presumed Reactivity

Chicken,

Rat

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 48 (USP48) is a member of the C19 peptidase family involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. USP48 is involved in the activation of NF-kappa B via its interaction with RELA and TRAF2.

84196

USP48

ubiquitin specific peptidase 48

Q86UV5

Ubiquitin carboxyl-terminal hydrolase 48

Alternate Names

deubiquitinating enzyme 48; RAP1GA1; ubiquitin carboxyl-terminal hydrolase 48; ubiquitin specific protease 31; ubiquitin thioesterase 48; ubiquitin thiolesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; ubiquitin-specific-processing protease 48; USP31

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.