/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-STRAP Antibody
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Primary Antibodies  

Rabbit anti-STRAP Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (1)
Target:

STRAP

Reactivity:

Human

,

Mouse

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 300 and 350

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Serine-threonine kinase receptor-associated protein (STRAP) plays a role in the cellular distribution of the SMN complex. It negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3F4].

11171

STRAP

serine/threonine kinase receptor associated protein

Q9Y3F4

Serine-threonine kinase receptor-associated protein

Alternate Names

MAP activator with WD repeats; MAWD; PT-WD; serine-threonine kinase receptor-associated protein; unr-interacting protein; UNRIP; WD-40 repeat protein PT-WD

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.