/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-SA2 Antibody
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Primary Antibodies  

Rabbit anti-SA2 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (1)
Target:

SA2

Reactivity:

Human

Applications:

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1125 and 1175

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

SA2 is a component of the multisubunit cohesin complex. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensure proper segregation of chromosomes. Cohesin must dissociate from sister chromatids during prophase and metaphase so that they can segregate to opposite poles of the cell during anaphase. As part of the cohesin complex, SA2 appears to play a role in cohesin dissociation required for sister chromatid separation. Interestingly, SA2 has been demonstrated to also exhibit transcriptional regulatory activity through an association with NF-kappaB.

10735

STAG2

stromal antigen 2

Q8N3U4

Cohesin subunit SA-2

Alternate Names

bA517O1.1; cohesin subunit SA-2; SA2; SA-2; SCC3 homolog 2; SCC3B; Stromal antigen 2

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.