Rabbit anti-RAD23B IHC Antibody Affinity Purified
Catalog #
RAD23B
Human
IHC
,IHC-IF
Rabbit
Polyclonal
Whole IgG
Between 359 and 409
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Guinea Pig,
Mouse,
Horse,
Zebra Finch,
Dog,
Chicken,
Pig,
Rabbit,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
Antibody was affinity purified using an epitope specific to RAD23B immobilized on solid support.
The epitope recognized by IHC-00663 maps to a region between residue 359 and 409 of human UV excision repair protein RAD23 homolog using the numbering given in entry NP_002865.1 (GeneID 5887).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to RAD23B immobilized on solid support.
The epitope recognized by IHC-00663-T maps to a region between residue 359 and 409 of human UV excision repair protein RAD23 homolog using the numbering given in entry NP_002865.1 (GeneID 5887).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. RAD23B was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
UV excision repair protein RAD23 homolog B
Alternate Names
HHR23B; HR23B; P58; RAD23, yeast homolog of, B; UV excision repair protein RAD23 homolog B; XP-C repair complementing complex 58 kDa; XP-C repair complementing protein; XP-C repair-complementing complex 58 kDa protein
Applications
