Rabbit anti-PTEN Recombinant Monoclonal Antibody [BLR270L]
Catalog #
PTEN
Human
,Mouse
,Rat
WB
Rabbit
Recombinant Monoclonal
BLR270L
Whole IgG
between 353 and 403 (C-term)
IgG
Unconjugated
Purified
Product Details
Rat,
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
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Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
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PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling.
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Alternate Names
10q23del; BZS; CWS1; DEC; GLM2; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin-like protein; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase; PTEN1; PTENbeta; TEP1
Applications