Rabbit anti-PSMD2 Antibody Affinity Purified
Catalog #
PSMD2
Human
,Mouse
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 50 and 100
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Bovine,
Rat
Human
2 - 8 °C
1 year from date of receipt
PSMD2 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 2] is a subunit of the 26 S proteasome. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD2 is a subunit of the 19S regulator lid, which is responsible for substrate recognition and binding [taken from NCBI Entrez Gene (Gene ID: 5708)].
26S proteasome non-ATPase regulatory subunit 2
Alternate Names
26S proteasome non-ATPase regulatory subunit 2; 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; 55.11 protein; P97; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; protein 55.11; RPN1; S2; TNFR-associated protein 2; TRAP2; tumor necrosis factor type 1 receptor-associated protein 2
Applications