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Rabbit anti-Prohibitin IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

Prohibitin

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 222 and 272

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Cat,

Guinea_pig,

Mouse,

Dog,

Pig,

Rabbit,

Bovine,

Monkey,

Rat

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

Prohibitin (PHB) has been identified as a tumor suppressor protein that can repress E2F-mediated transcription and arrest cell cycle progression. It has recently been shown to associate with members of the minichromosome maintenance complex such as MCM2, MCM5, and MCM7 and therefore is thought to impart its growth inhibitory effects via association with the replication machinery. Prohibitin is also implicated in regulating mitochondrial respiration and playing a role in aging.

5245

PHB

prohibitin

P35232

Prohibitin

Alternate Names

epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; HEL-215; HEL-S-54e; PHB1; prohibitin

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer or tris-EDTA pH9.0 buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.