Rabbit anti-PDZ-GEF2 Antibody Affinity Purified
Catalog #
PDZ-GEF2
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1551 and 1601
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
PDZ-GEF2 is a guanine nucleotide exchange factor (GEF) for Rap GTPases. It contains one PDZ-signaling domain, a Ras-association (RA) domain, and a region related to a cyclic nucleotide binding domain (RCBD). PDZ-GEF1 functions to catalyze the exchange of GDP for GTP and activate Rap1A, Rap1B, and Rap2B GTPase activity. PDZ-GEF2 has been shown to activate Rap1A and Rap1B to promote the maturation of cell-cell adherens junctions.
Rap guanine nucleotide exchange factor 6
Alternate Names
KIA001LB; PDZ domain containing guanine nucleotide exchange factor (GEF) 2; PDZ domain-containing guanine nucleotide exchange factor 2; PDZ domain-containing guanine nucleotide exchange factor I; PDZGEF2; PDZ-GEF2; RAGEF2; RA-GEF-2; Rap guanine nucleotide exchange factor (GEF) 6; rap guanine nucleotide exchange factor 6
Applications