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Primary Antibodies  

Rabbit anti-PAPD1 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (1)
Target:

PAPD1

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 532 and 582

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

PAPD1 (mitochondrial poly(A) polymerase) is a polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. PAPD1 can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). It plays a role in replication-dependent histone mRNA degradation. It may be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated and might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA [taken from NCBI Entrez Gene (Gene ID: 55149)].

55149

MTPAP

mitochondrial poly(A) polymerase

Q9NVV4

Poly(A) RNA polymerase, mitochondrial

Alternate Names

mtPAP; PAP; PAP-associated domain-containing protein 1; PAPD1; poly(A) RNA polymerase, mitochondrial; polynucleotide adenylyltransferase; SPAX4; TENT6; terminal uridylyltransferase 1; TUTase 1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.