Rabbit anti-Nicastrin Antibody
Catalog #
Nicastrin
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 659 and 709
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Nicastrin is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92542].
Alternate Names
anterior pharynx-defective 2; ATAG1874; nicastrin
Applications