Rabbit anti-Neurofilament-L Recombinant Monoclonal Antibody [BLR224K]
Catalog #
Neurofilament-L
Human
,Mouse
,Rat
ICC
,IHC
,IP
,WB
Rabbit
Recombinant Monoclonal
BLR224K
Whole IgG
between 150 and 200
IgG
Unconjugated
Purified
Product Details
Rat,
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Request Formulation Change
Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Request Formulation Change
Neurofilaments are type IV intermediate filament heteropolymers composed of light (L), medium (M), and heavy (H) chains. Neurofilaments are a component of the axon cytoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. Mutations in the Neurofilament-L cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. [taken from NCBI Entrez Gene (Gene ID: 4747)].
Alternate Names
68 kDa neurofilament protein; CMT1F; CMT2E; CMTDIG; light molecular weight neurofilament protein; neurofilament light polypeptide; neurofilament protein, light chain; neurofilament subunit NF-L; neurofilament triplet L protein; neurofilament, light polypeptide 68kDa; NF68; NFL; NF-L; PPP1R110; protein phosphatase 1, regulatory subunit 110
Applications