Rabbit anti-NBS1 Antibody
Catalog #
NBS1
Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 701 and 751
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse
Rat
Mouse
2 - 8 °C
1 year from date of receipt
Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.
Alternate Names
cell cycle regulatory protein p95; Nbs1; nibrin; nijmegen breakage syndrome protein 1 homolog
Applications