/ ANTIBODIES/ANTISERA / MAPK Pathway Antibodies / Rabbit anti-MSK2 Antibody
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MAPK Pathway Antibodies  

Rabbit anti-MSK2 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (1)
Target:

MSK2

Reactivity:

Human

,

Mouse

Applications:

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 722 and 772

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

MSK1 is a serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). MSK1 Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. MSK1 also phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75582].

8986

RPS6KA4

ribosomal protein S6 kinase A4

O75676

Ribosomal protein S6 kinase alpha-4

Alternate Names

90 kDa ribosomal protein S6 kinase 4; mitogen- and stress-activated protein kinase 2; MSK2; nuclear mitogen- and stress-activated protein kinase 2; ribosomal protein kinase B; ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; RSKB; RSK-B; S6K-alpha-4

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.