Rabbit anti-Metnase Antibody
Catalog #
Metnase
Human
IP
Rabbit
Polyclonal
Whole IgG
Between 225 and 275
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Metnase is also known as Histone-lysine N-methyltransferase SETMAR. Metnase is a histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Metanase specifically mediates dimethylation of H3 'Lys-36', and has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Metnase possessess DNA nicking activity and in vivo end joining activity, and it may mediate genomic integration of foreign DNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q53H47].
Histone-lysine N-methyltransferase SETMAR
Alternate Names
Histone-lysine N-methyltransferase; histone-lysine N-methyltransferase SETMAR; Mar1; METNASE; SET domain and mariner transposase fusion gene-containing protein; SET domain and mariner transposase fusion protein
Applications