Rabbit anti-Met Recombinant Monoclonal Antibody [BLR283L]
Catalog #
Met
Human
Flow Cyt
,ICC
,IHC
,IP
,WB
Rabbit
Recombinant Monoclonal
BLR283L
Whole IgG
between 1340 and 1390 (C-term)
IgG
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Recombinant antibody was purified from cell culture supernatant.
Immunogen was a peptide representing a region between residue 1340 and the C-terminus (residue 1390) of human Hepatocyte growth factor receptor (aka Met) using the numbering given in entry NP_000236.2 (Gene ID 4233).
The proto-oncogene MET is a member of the receptor tyrosine kinase family of proteins. The preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. [taken from NCBI Entrez Gene (Gene ID: 4233)].
Alternate Names
AUTS9;c-Met;DFNB97;hepatocyte growth factor receptor;HGF receptor;HGF/SF receptor;HGFR;proto-oncogene c-Met;RCCP2;scatter factor receptor;SF receptor;tyrosine-protein kinase Met
Applications