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Rabbit anti-MARK3 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

MARK3

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 525 and 575

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

MARK3 (Microtubule-affinity regulating kinase 3) is also known as PAR-1a (partition-defective 1a) and is a member of a family of kinases that plays a role in cell polarity and cell-cycle control. There are four PAR-1/MARK isoforms encoded by independent genes: MARK1 (PAR-1c), MARK2 (PAR-1b/EMK), MARK3(PAR-1a), and MARK4 (PAR-1d/MARKL1). MARK isoforms phosphorylates microtubule associated proteins (MAPs) such as MAP2, MAP4, and tau to regulate their association with microtubules.

4140

MARK3

microtubule affinity regulating kinase 3

P27448

MAP/microtubule affinity-regulating kinase 3

Alternate Names

cdc25C-associated protein kinase 1; CTAK1; C-TAK1; ELKL motif kinase 2; EMK-2; KP78; MAP/microtubule affinity-regulating kinase 3; PAR1A; Par-1a; protein kinase STK10; ser/Thr protein kinase PAR-1; serine/threonine-protein kinase p78

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.