/ ANTIBODIES/ANTISERA / MAPK Pathway Antibodies / Rabbit anti-HPK1 Antibody
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MAPK Pathway Antibodies  

Rabbit anti-HPK1 Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

HPK1

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 550 and 600

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

HPK1 (hematopoietic progenitor kinase 1) is a serine/threonine kinase specific to hematopoietic cells including progenitor cells. It is related to the yeast STE20 kinase and is involved in many signaling cascades including the MAPK and JNK/SAPK signaling pathway. HPK1 binds many adaptor proteins which link HPK1 to cell surface receptors and direct its downstream signals.

11184

MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

Q92918

Mitogen-activated protein kinase kinase kinase kinase 1

Alternate Names

Hematopoietic progenitor kinase; hematopoietic progenitor kinase 1; HPK1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; mitogen-activated protein kinase kinase kinase kinase 1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.