Bethyl Laboratories® Rabbit anti-GIT2 IHC Antibody, Affinity Purified - 100 µl (50+ slides)
Catalog #
GIT2
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 500 and 550
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Guinea Pig,
Mouse,
Horse,
Zebra Finch,
Turkey,
Dog,
Chicken,
Pig,
Rabbit,
X. laevis,
X. tropicalis,
Bovine,
Monkey,
Rat
Human
2 - 8 °C
1 year from date of receipt
G-protein-coupled receptor kinase interactor 1 (GIT1) and G-protein-coupled receptor kinase interactor 2 (GIT2) are GTPase-activating proteins for ADP-ribosylation (Arf) GTPases. GIT1 and GIT2 regulate Arf activity and the sequestration of activated G protein-coupled receptors from the surface of the cell. These activities have effects on multiple cellular processes such as cell migration, T-cell activation, and centrosome dynamics. Both GIT proteins also serve as scaffolds to link signaling molecules.
Alternate Names
ARF GAP GIT2; ARF GTPase-activating protein GIT2; CAT2; CAT-2; cool-associated, tyrosine phosphorylated protein 2; cool-interacting tyrosine-phosphorylated protein 2; G protein-coupled receptor kinase interacting ArfGAP 2; G protein-coupled receptor kinase-interactor 2; GRK-interacting protein 2; Paxillin kinase linker; PKL
Applications