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Rabbit anti-gamma-H2AX Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
gamma-H2AX
Reactivity:
Human
,Mouse
Applications:
ICC-IF
,IHC
,WB
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
surrounding serine 140
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (1000 µg/ml)
10 µl (1000 µg/ml)
Product Details
Specifications
Verified Reactivity
Mouse,
Human
Antigen Species
Human
Concentration
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to gamma-H2AX immobilized on solid support.
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
The epitope recognized by A300-081A maps to a region surrounding phosphorylated serine 140 of human histone H2AX using the numbering given in entry NP_002096.1 (GeneID 3014).
Antibody was affinity purified using an epitope specific to gamma-H2AX immobilized on solid support.
The epitope recognized by A300-081A-T maps to a region surrounding phosphorylated serine 140 of human histone H2AX using the numbering given in entry NP_002096.1 (GeneID 3014).
Additional Product Information
H2AX is a member of the histone H2A family. The four core histones involved in the formation of the nucleosome structure of compacted chromatin are H2A, H2B, H3, and H4. H2AX may function to facilitate DNA repair, and recent studies have shown that H2AX is required for the maintenance of genomic stability. Gamma H2AX is the phosphorylated form of H2AX that results in response to DNA damage.
Alternate Names
H2A.X; H2A/X; H2AX; H2AX histone; histone H2A.x; histone H2AX
Applications
