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Rabbit anti-FUSIP1 IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

FUSIP1

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 133 and 183

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Mouse,

Pig,

Bovine,

Rat

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

FUSIP1 (FUS-interacting protein 1) was originally identified in a two-hybrid screen for partners of the TLS (translocated in liposarcoma) protein also known as FUS. FUSIP1 is a splicing factor of the serine-arginine (SR) family of proteins. It functions as a splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. FUSIP1 seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70, and it is required for splicing repression in M-phase cells and after heat shock [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75494].

10772

SRSF10

serine and arginine rich splicing factor 10

O75494

Serine/arginine-rich splicing factor 10

Alternate Names

40 kDa SR-repressor protein; FUS-interacting protein (serine-arginine rich) 2; FUS-interacting serine-arginine-rich protein 1; FUSIP1; FUSIP2; neural-salient SR protein; NSSR; PPP1R149; protein phosphatase 1, regulatory subunit 149; serine/arginine-rich splicing factor 10; serine-arginine repressor protein (40 kDa); SFRS13; SFRS13A; splicing factor SRp38; splicing factor, arginine/serine-rich 13; splicing factor, arginine/serine-rich 13A; SR splicing factor 10; SRp38; SRrp40; TASR; TASR1; TASR2; TLS-associated protein TASR; TLS-associated protein with Ser-Arg repeats; TLS-associated protein with SR repeats; TLS-associated serine-arginine protein

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.