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Rabbit anti-Fen1 IHC Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

Fen1

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 250 and 300

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Presumed Reactivity

Horse,

Sheep,

Pig,

Bovine

Antigen Species

Human

Concentration
500 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

Flap endonuclease 1 (Fen1) is a member of the XPG/RAD2 endonuclease family. Fen1 functions primarily as an endonuclease that removes 5’-overhangs during base-excision DNA repair and lagging strand DNA synthesis. For these processes Fen1 interacts with PCNA and the 9-1-1 DNA repair complex. Fen1 also possesses 5’ to 3’ exonuclease activity as well as RNase H activity.

2237

FEN1

flap structure-specific endonuclease 1

P39748

Flap endonuclease 1

Alternate Names

DNase IV; FEN-1; flap endonuclease 1; Flap structure-specific endonuclease 1; hFEN-1; Maturation factor 1; maturation factor-1; MF1; RAD2

Applications

Epitope exposure is recommended.

Epitope exposure with citrate buffer will enhance staining.

Overnight incubation at room temperature is recommended.

Likely to work with frozen sections.