/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-FASN Antibody
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Primary Antibodies  

Rabbit anti-FASN Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (2)
Target:

FASN

Reactivity:

Human

Applications:

IHC

,

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 1175 and 1225

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

Fatty acid synthase (FASN) is a multifunctional protein that is mainly involved in catalyzing the synthesis of long-chain fatty acids. FASN has recently been viewed as an important protein involved in carcinogenesis as it has been found to be constitutively active in subsets of carcinomas and is associated with a poor prognosis. The inhibition of FASN activity in cancer cells promotes apoptosis and thus may play a role in maintaining cancer cell survival.

2194

FASN

fatty acid synthase

P49327

Fatty acid synthase

Alternate Names

Acyl-carrier-protein S-acetyltransferase; Acyl-carrier-protein S-malonyltransferase; 3-hydroxyacyl-acyl-carrier-protein dehydratase; 3-oxoacyl-acyl-carrier-protein reductase; Enoyl-acyl-carrier-protein reductase; FAS; fatty acid synthase; OA-519; Oleoyl-acyl-carrier-protein hydrolase; SDR27X1; short chain dehydrogenase/reductase family 27X, member 1

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.