Rabbit anti-EYA3 Antibody
Catalog #
EYA3
Human
IP
Rabbit
Polyclonal
Whole IgG
between 30 and 60
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q99504].
Alternate Names
eyes absent 3; eyes absent homolog 3
Applications