Rabbit anti-EXOSC5 Antibody Affinity Purified
Catalog #
EXOSC5
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
EXOSC5 (exosome complex component RRP46) is a non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NQT4].
Alternate Names
chronic myelogenous leukemia tumor antigen 28; exosome complex component RRP46; exosome complex exonuclease RRP46; Exosome component 5; exosome component Rrp46; hRrp46p; p12B; ribosomal RNA-processing protein 46; RRP41B; RRP46; Rrp46p
Applications