Rabbit anti-DBC1/p30 DBC Antibody
Catalog #
DBC1/p30 DBC
Human
,Mouse
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 650 and 700
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
Human
2 - 8 °C
1 year from date of receipt
The DBC1 (Deleted in Breast Cancer Gene 1 protein) gene is located in a region frequently deleted in breast cancers. In its uncleaved form, DBC1 is localized to the nucleus. Upon cleavage by caspase activity, DBC1 becomes localized to the cytoplasm and functions to promote apoptosis. DBC1 has also been found to bind directly to the estrogen receptor alpha (ERalpha) hormone binding domain to modulate ERalpha expression and mediate hormone-independent breast cancer cell survival.
Cell cycle and apoptosis regulator protein 2
Alternate Names
cell cycle and apoptosis regulator protein 2; cell division cycle and apoptosis regulator protein 2; DBC.1; DBC1; DBC-1; DBIRD complex subunit KIAA1967; deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; KIAA1967; NET35; p30 DBC; p30 DBC protein; p30DBC
Applications