/ ANTIBODIES/ANTISERA / Primary Antibodies / Rabbit anti-DAB2IP Antibody
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Primary Antibodies  

Rabbit anti-DAB2IP Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Citations (3)
Target:

DAB2IP

Reactivity:

Human

Applications:

IP

,

WB

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 950 and 1000

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (200 µg/ml)

10 µl (200 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
200 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Additional Product Information

DAB2-interacting protein (DAB2IP) functions as a Ras GTPase-activating protein. Through its interaction with MAP3K5, it disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. DAB2IP also Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. DAB2IP may act as a tumor suppressor gene [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5VWQ8].

153090

DAB2IP

DAB2 interacting protein

Q5VWQ8

Disabled homolog 2-interacting protein

Alternate Names

AF9Q34; AIP1; AIP-1; ASK1-interacting protein 1; ASK-interacting protein 1; DAB2 interaction protein; DAB2-interacting protein; DIP1/2; disabled homolog 2-interacting protein; DOC-2/DAB2 interactive protein; DOC-2/DAB-2 interactive protein; nGAP-like protein

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.