Rabbit anti-Cul3 Antibody Affinity Purified
Catalog #
Cul3
Human
,Mouse
WB
Rabbit
Polyclonal
Whole IgG
between 718 and 768
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Mouse,
Human
X. laevis,
X. tropicalis,
Rat
Human
2 - 8 °C
1 year from date of receipt
Cul3 is a member of the cullin group of proteins and functions as a scaffold to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. Cul3 and its associated ubiquitin ligase activity are essential for mitotic division and required for correct alignment of chromosomes and the completion of cytokinesis. Aurora B is a substrate of Cul3-based E3 ubiquitin ligase activity.
Alternate Names
CUL-3; cullin-3; PHA2E
Applications