Rabbit anti-CDCA2 Antibody Affinity Purified
Catalog #
CDCA2
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 200 and 250
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
CDCA2 is a regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q69YH5].
Alternate Names
cell division cycle-associated protein 2; PPP1R81; protein phosphatase 1, regulatory subunit 81; recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
Applications