Rabbit anti-CBFA2T2 Antibody Affinity Purified
Catalog #
CBFA2T2
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 554 and 604
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
CBFA2T2 may function in a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). CBFA2T2 may thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. CBF2T2 may be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O43439].
Alternate Names
core-binding factor, runt domain, alpha subunit 2; translocated to, 2; EHT; ETO homolog on chromosome 20; ETO homologous on chromosome 20; MTG8-like protein; MTG8-related protein 1; MTGR1; myeloid translocation gene-related protein 1; myeloid translocation-related protein 1; p85; protein CBFA2T2; ZMYND3
Applications