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Primary Antibodies  

Rabbit anti-CASC5 Antibody

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Citations (1)
Target:

CASC5

Reactivity:

Human

Applications:

IP

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

between 250 and 300

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (1000 µg/ml)

10 µl (1000 µg/ml)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


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Additional Product Information

Cancer susceptibility candidate gene 5 protein (CASC5) is predominantly expressed in testis and widely expressed in various human tumor cell lines and primary tumors from various tissues and organs. CASC5 is most frequently expressed in lung cancer and has been identified as a fusion-partner of the mixed lineage leukemia (MLL) gene, a gene often activated by chromosomal translocation in leukemias. CASC5 has also been identified as a component of the Mis12 kinetochore complex that is required for proper chromosome segregation.

57082

KNL1

kinetochore scaffold 1

Q8NG31

Protein CASC5

Alternate Names

AF15Q14; ALL1-fused gene from chromosome 15q14 protein; Blinkin; blinkin, bub-linking kinetochore protein; Bub-linking kinetochore protein; cancer susceptibility candidate 5; cancer susceptibility candidate gene 5 protein; cancer/testis antigen 29; CASC5; CT29; D40; hKNL-1; hSpc105; kinetochore null 1 homolog; kinetochore scaffold 1; kinetochore-null protein 1; MCPH4; microcephaly, primary autosomal recessive 4; PPP1R55; Protein CASC5; Protein D40/AF15q14; protein phosphatase 1, regulatory subunit 55; Spc7

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.