Rabbit anti-CAD IHC Antibody Affinity Purified
Bethyl Laboratories
Catalog #
Validated
Target:
CAD
Reactivity:
Human
Applications:
IHC
,IHC-IF
Host:
Rabbit
Clonality:
Polyclonal
Format:
Whole IgG
Immunogen:
Between 1650 and 1700
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Antigen Affinity Purified
100 µl (50+ slides)
10 µl (5+ slides)
Product Details
Specifications
Verified Reactivity
Human
Presumed Reactivity
Guinea Pig,
Mouse,
Dog,
Pig,
Rabbit,
Monkey,
Rat
Antigen Species
Human
Concentration
250 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Production Procedures
Antibody was affinity purified using an epitope specific to CAD immobilized on solid support.
The epitope recognized by IHC-00280 maps to a region between residue 1650 and 1700 of human carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase using the numbering given in entry NP_004332.2 (GeneID 790).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Antibody was affinity purified using an epitope specific to CAD immobilized on solid support.
The epitope recognized by IHC-00280-T maps to a region between residue 1650 and 1700 of human carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase using the numbering given in entry NP_004332.2 (GeneID 790).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
CAD is an enzyme involved in the first three steps of the de novo synthesis of pyrimidine nucleotides. CAD exhibits multiple catalytic activities and is described as a “fusion” protein that can function as a carbamoylphosphate synthetase, aspartate transcarbamoylase, and dihydroorotase. CAD has been shown to be phosphorylated by mitogen-activated protein (MAP) kinase and protein kinase A (PKA) for the coordination of cell cycle progression and pyrimidine biosynthesis.
CAD protein
Alternate Names
Aspartate carbamoyltransferase; CAD protein; CAD trifunctional protein; CDG1; ZDihydroorotase; EIEE50; GATD4; multifunctional protein CAD
Applications
