Rabbit anti-BubR1 Antibody Affinity Purified
Catalog #
BubR1
Human
IHC
,IP
,WB
Rabbit
Polyclonal
Whole IgG
between 1 and 50
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
BubR1 is cell cycle checkpoint kinase and component of the spindle checkpoint machinery. BubR1 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. BubR1 is part of the mitotic checkpoint complex that also includes Bub3, Mad2, and Cdc20. In this trimer BubR1 functions to inhibit the anaphase promoting complex (APC) that promotes chromosome segregation. BubR1 is suggested to be a paralog of Bub1.
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Alternate Names
Bub1A; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 homolog beta; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Applications