Rabbit anti-Bub3 Antibody Affinity Purified
![bethyl](http://cdn-tp1.mozu.com/31165-51694/cms/51694/files/bethyl.png)
Catalog #
Bub3
Human
IHC
,WB
Rabbit
Polyclonal
Whole IgG
between 275 and 325
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Mouse,
Bovine
Human
2 - 8 °C
1 year from date of receipt
Bub3 is an adaptor protein and component of the spindle checkpoint machinery. Bub3 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. Bub3 forms a constitutive complex with Bub1. Bub3 has been demonstrated to also function as a transcriptional repressor in association with Cdc20 and histone deacetylases.
Alternate Names
BUB3 budding uninhibited by benzimidazoles 3 homolog; BUB3L; budding uninhibited by benomyl; budding uninhibited by benzimidazoles 3 homolog; hBUB3; mitotic checkpoint component; mitotic checkpoint protein BUB3; testicular tissue protein Li 27
Applications