Rabbit anti-B-Myb IHC Antibody
Catalog #
B-Myb
Human
IHC
Rabbit
Polyclonal
Whole IgG
Between 450 and 500
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Guinea_pig,
Horse,
Dog,
Pig,
Rabbit,
Bovine,
Monkey
Human
2 - 8 °C
1 year from date of receipt
B-myb is transcription factor involved in multiple cellular processes such as cell survival, proliferation, and differentiation. B-myb was identified in a low-stringency screen of a T-cell cDNA library probed with a C-myb probe. C-myb is a cellular proto-oncogene highly conserved in vertebrates and invertebrates. The chicken c-myb proto-oncogene was the first ortholog discovered. Investigation of the origins of the avian myeloblastosis virus (AMV) led to the discovery that the AMV genome contained transduced sequences from normal chicken cellular DNA that resulted in a viral oncogenic version (v-myb) of the c-myb gene. B-myb is cell cycle regulated and expressed in all proliferating cells. Recent studies show that it is the only myb family member detected in embryonic stem cells and is essential to cell cycle progression and genomic stability.
Alternate Names
BMYB; B-MYB; myb-like protein 2; myb-related protein B; v-myb avian myeloblastosis viral oncogene homolog-like 2; v-myb myeloblastosis viral oncogene homolog-like 2
Applications
