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Rabbit anti-AXL Recombinant Monoclonal Antibody [BLR222K]

Bethyl Laboratories®
Bethyl Laboratories®

Catalog #

Validated
Target:

AXL

Reactivity:

Human

,

Mouse

Host:

Rabbit

Clonality:

Recombinant Monoclonal

Clone:

BLR222K

Format:

Whole IgG

Immunogen:

residues 33-440(ECD)

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Purified

100 µl (50+ tests)

10 µl (5+ tests)

Product Details

Specifications
Verified Reactivity

Mouse,

Human

Antigen Species

Human

Concentration
1000 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free


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Additional Product Information

Axl is a receptor tyrosine kinase (RTK) that binds the ligand Gas6 (growth-arrest specific gene). It is part of a sub-family of RTKs that includes Axl, SKY and MER. The Axl gene was first identified as a transforming cDNA isolated from patients with chronic myelogenous leukemia. Axl-Gas6 signaling is implicated in cellular responses such as cell survival, proliferation, migration, and adhesion, and it may be involved in cancer progression.

558

AXL

AXL receptor tyrosine kinase

P30530

Tyrosine-protein kinase receptor UFO

Alternate Names

ARK; AXL oncogene; AXL transforming sequence/gene; JTK11; Tyro7; tyrosine-protein kinase receptor UFO; UFO

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots of cell lysates are performed using Goat anti-Rabbit IgG Heavy and Light Chain Antibody (Cat. No. A120-101P).

Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.