Rabbit anti-ASPM IHC Antibody Affinity Purified

bethyl
Bethyl Laboratories

Catalog #

Validated
Target:

ASPM

Reactivity:

Human

Host:

Rabbit

Clonality:

Polyclonal

Format:

Whole IgG

Immunogen:

Between 3425 and C-term

Isotype:

IgG

Conjugate:

Unconjugated

Purity:

Antigen Affinity Purified

100 µl (50+ slides)

10 µl (5+ slides)

Product Details

Specifications
Verified Reactivity

Human

Antigen Species

Human

Concentration
250 µg/ml
Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State
Liquid
Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide


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Production Procedures

Antibody was affinity purified using an epitope specific to ASPM immobilized on solid support.

The epitope recognized by IHC-00058 maps to a region between residue 3425 and the C-terminus (residue 3477) of human ASP (Abnormal Spindle)-like, Microcephaly Associated using the numbering given in entry NP_060606.2 (GeneID 259266).

Antibody was affinity purified using an epitope specific to ASPM immobilized on solid support.

The epitope recognized by IHC-00058-T maps to a region between residue 3425 and the C-terminus (residue 3477) of human ASP (Abnormal Spindle)-like, Microcephaly Associated using the numbering given in entry NP_060606.2 (GeneID 259266).

Additional Product Information

ASPM (abnormal spindle-like microcephaly associated) is also known as MCPH5 (autosomal recessive primary microcephaly 5). Defects in ASPM are the cause of microcephaly primary type 5 or microcephaly vera, an autosomal recessive disease characterized by reduced head circumference, small cerebral cortex, and reduced brain weight. At the cellular level, MCPH5 is important to mitotic spindle function and may play a preferential role in prenatal neurogenesis.

259266

ASPM

abnormal spindle microtubule assembly

Q8IZT6

Abnormal spindle-like microcephaly-associated protein

Alternate Names

Abnormal spindle protein homolog; abnormal spindle-like microcephaly-associated protein; ASP; asp (abnormal spindle) homolog, microcephaly associated; Asp homolog; Calmbp1; MCPH5

Applications

Formaldehyde-fixed cells: 1:100 - 1:500:

Permeabilization with Triton-X 100 is recommended.

Likely to work with frozen sections.

In some cases, the antibody may be diluted further than indicated.