Rabbit anti-ARAP3 Antibody
Catalog #
ARAP3
Human
IP
Rabbit
Polyclonal
Whole IgG
Between 1200 and 1250
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
ARAP3 is a phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. It is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. It can also be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. ARAP3 acts on ARF6, RAC1, RHOA and CDC42. ARAP3 plays a role in the internalization of anthrax toxin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8WWN8].
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Alternate Names
Arf and Rho GAP adapter protein 3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3; centaurin-delta-3; CENTD3; Cnt-d3; DRAG1; phosphoinositide binding protein; PtdIns(3,4,5)P3-binding protein
Applications