Mouse anti-Progesterone Receptor Monoclonal Antibody [188]
Catalog #
Progesterone Receptor
Human
Flow Cyt
,ICC
,IHC
,IP
,WB
COMET™
Mouse
Monoclonal
188
Whole IgG
IgG1
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Monoclonal antibody was purified from cell culture supernatant.
Immunogen was a recombinant protein representing human Progesterone Receptor.
The progesterone receptor (PR) is a member of the steroid receptor superfamily that binds progesterone and is critical to all aspects of reproductive development and the establishment and maintenance of pregnancy. When bound by progesterone, PR enters the nucleus to function in gene-specific transcriptional activation. Progesterone receptor expression is regulated by estrogen. Recent studies have found that the status of the progesterone receptor in breast tumors may be an indicator of how tumors will respond to tamoxifen treatment.
Alternate Names
NR3C3; nuclear receptor subfamily 3 group C member 3; PR; progesterone receptor
Applications