Mouse anti-Estrogen Receptor Alpha Monoclonal Antibody [119-13]
Catalog #
Estrogen Receptor Alpha
Human
Flow Cyt
,ICC
,IHC
,IP
,WB
Mouse
Monoclonal
119-13
Whole IgG
recombinant human Estrogen Receptor Alpha
IgG1
Unconjugated
Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
The estrogen receptor (ER) is the steroid-hormone nuclear receptor that binds estrogen and functions to activate genes involved in a variety of biological processes. Two forms of the ER, ER alpha and ER beta, are encoded by independent genes, and each plays different roles in gene regulation. Additional variants of ER beta have also been reported; these include ERb2, ERb3, ERb4, and ERb5. All forms of the ER have the ability to heterodimerize with each other. Differences in localization and concentrations as well as heterodimerization among the variants may serve to achieve distinct cell and tissue responses. ER alpha generally functions as an activator of transcription while ER beta functions as a repressor.
Alternate Names
E2 receptor alpha; ER; Era; ER-alpha; ESR; ESRA; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; ESTRR; NR3A1; nuclear receptor subfamily 3 group A member 1; oestrogen receptor alpha
Applications
