Rabbit anti-I kappa B-beta Antibody
Catalog #
I kappa B-beta
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
between 306 and 356
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
Activity of the transcription factor NF-kappa B is regulated by inhibitor proteins that interact with NF-kappa B and inhibit their DNA binding activity. These inhibitor proteins are members of the I kappa B family of proteins and include I kappa B-beta, I kappa B-delta/NF-kappa B2/p100, I kappa B-gamma/NF-kappa Bp105, I kappa B-epsilon, I kappa B-zeta, and Bcl3. Association with I kappa B proteins sequesters NF-kappa B in the cytoplasm to regulate its activity. The Phosphorylation of I kappa B by the I kappa B kinase complex (IKK) results in the ubiquitination and degradation of I kappa B and the release and translocation of NF-kappa B to the nucleus.
Alternate Names
ikappaBbeta; I-kappa-B-beta; IKBB; ikB-B; ikB-beta; NF-kappa-B inhibitor beta; NF-kappa-BIB; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP9; TRIP-9
Applications