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Rabbit anti-PCNA Recombinant Monoclonal Antibody [BLR075G]
Bethyl Laboratories
Catalog #
Validated
Target:
PCNA
Reactivity:
Human
Applications:
Flow Cyt
,ICC
,IHC
,IHC-IF
,WB
Platforms:
COMET™
,PhenoImager™ HT
Host:
Rabbit
Clonality:
Recombinant Monoclonal
Clone:
BLR075G
Format:
Whole IgG
Immunogen:
Between 211 and C-terminus
Isotype:
IgG
Conjugate:
Unconjugated
Purity:
Purified
100 µl (50+ tests)
10 µl (5+ tests)
100 µg (BSA-Free)
Product Details
Specifications
Verified Reactivity
Human
Antigen Species
Human
Concentration
10 µg/ml
1000 µg/ml
Storage
2 - 8 °C
Shelf Life
1 year from date of receipt
Physical State
Liquid
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Request Formulation Change
Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free
Request Formulation Change
Production Procedures
Recombinant antibody was purified from cell culture supernatant.
Immunogen was a peptide representing a region between residue 225 and the C-terminus (residue 261) of human Proliferating cell nuclear antigen using the numbering given in entry NP_002583.1 (Gene ID 5111).
Additional Product Information
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.
Alternate Names
ATLD2; cyclin; DNA polymerase delta auxiliary protein; PCNA; proliferating cell nuclear antigen
Applications
