With the advancement of immunotherapeutics, the urge to understand the tumor microenvironment has never been more pressing. Molecular histopathology has recently been shifting from single-marker immunohistochemistry towards multiplexed marker detection. Multiplex immunohistochemistry maximizes the amount of data acquired from an individual sample. Recent advances in multiplex immunohistochemistry and multispectral imaging facilitate accurate simultaneous analysis of multiple tissue markers. Clinically, understanding of the tumor microenvironment, and subsequent selection of appropriately-targeted therapies, can be augmented by profiling and localizing immune checkpoint proteins. The applications of multiplex immunohistochemistry are numerous and span clinical, translational, and basic research applications.
Quickly detect multiple antigens in a single tissue section to gain a clear understanding of the tumor microenvironment without compromising samples with Bethyl PathPlex® panels. Each antibody has been validated for immunohistochemistry (IHC) and utilized in a multiplex format by our scientists via proprietary processes to ensure the highest quality.
Core panels are listed below. Additional antibodies can be purchased depending on your research needs.