TAK1-binding protein 3 (TAB3) is a binding and regulatory subunit of the transforming growth factor-beta-activated kinase 1 (TAK1). TAB3 functions as an adaptor that mediates IL1 and TNF signaling pathways. Additionally it plays a role in the activation of the NF-kappaB pathway by functioning as receptors that bind polyubiquitin chains for the regulation of kinase activity.
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
mitogen-activated protein kinase kinase kinase 7 interacting protein 3•
Mitogen-activated protein kinase kinase kinase 7-interacting protein 3•
NF-kappa-B-activating protein 1•
NFkB activating protein 1•
TAK1 binding protein 3•
TAK1-binding protein 3•
TGF-beta-activated kinase 1-binding protein 3•More...Less...