Spt16 Antibody

Spt16 is a Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is composed of two subunits: SSRP1 and Spt16. It is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, and then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y5B9].
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit
FACT complex subunit SPT16
:  CDC68 chromatin-specific transcription elongation factor 140 kDa subunit facilitates chromatin remodeling 140 kDa subunit facilitates chromatin transcription complex subunit SPT16 FACT FACT 140 kDa subunit FACTP140 FLJ10857 FLJ14010 hSPT16 SPT16 SPT16/CDC68 suppressor of Ty (S.cerevisiae) 16 homolog suppressor of Ty 16 homolog suppressor of Ty 16 homolog (S. cerevisiae) More... Less...
Product
Specifications
Ordering Information
Human
WB
Between 997 and 1047
$339
$229
$99