Sjogren syndrome antigen B (autoantigen La) (SS-B) is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus [taken from NCBI Entrez Gene (Gene ID: 6741)].
La ribonucleoprotein domain family, member 3•
lupus La antigen•
Lupus La protein•
sjoegren syndrome type B antigen•
Sjogren syndrome antigen B (autoantigen La)•