SPTY2D1 Antibody

SPT2, Suppressor of Ty (SPTY2D1) is a histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). It is required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). SPTY2D1 binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). It facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). SPTY2D1 modulates RNA polymerase 1-mediated transcription (By similarity) and binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q68D10].
SPT2 chromatin protein domain containing 1
Protein SPT2 homolog
:  DKFZp686I068 FLJ39441 Protein KU002155 Spt2 SPT2 domain-containing protein 1 SPT2, Suppressor of Ty, domain containing 1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
Ordering Information
Between 75 and 125