SENP3 Antibody

Sentrin-specific protease 3 (SENP3) functions as a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates.SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability, and also deconjugates SUMO2 and SUMO3 from CDCA8. SENP3 can function as a redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. SENP3 is required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9H4L4].
SENP3
SUMO1/sentrin/SMT3 specific peptidase 3
Sentrin-specific protease 3
:  DKFZP586K0919 DKFZp762A152 sentrin/SUMO-specific protease 3 Sentrin/SUMO-specific protease SENP3 SMT3IP1 SSP3 SUMO1/sentrin/SMT3 specific protease 3 SUMO-1-specific protease 3 Ulp1
Product
Specifications
Ordering Information
Human, Mouse
WB, IP, IHC
Between 1 and 50
$339
$229
$99
Human
WB, IP, IHC
Between 275 and 325
$339
$229
$99
Human, Mouse
WB, IP, IHC
Includes: 1 each of A303-139A and A303-140A
$472
Includes: 1 each of A303-139A and A303-140A