PPP4R3 Alpha Antibody

PPP4R3 is a binding partner of the PPP4C catalytic subunit of the PP4 serine/threonine protein phosphatase. PPP4C is structurally related to PP2AC but does not associate with the same regulatory subunits. PPP4C associates with either the PPP4R1 or PPP4R2 regulatory subunit. In addition to PPP4R1 and PPP4R2, PPP4R3 has also been identified as a regulator of PPP4C function. PP4R3 functions with PP4C in the control of recovery from DNA damage. PP4R3 may function by targeting PPP4 to sites of DNA damage via an interaction with Rad53 (CHK2). PP4R3 is the human homolog of the Dictylostelium SMEK (suppressor of MEK). SMEK has been shown to be involved in cell polarization and chemotaxis via an involvement in the MEK1/ERK1 signaling pathway. SMEK also functions by controlling PPP4C localization to nucleus.
PPP4R3A
protein phosphatase 4 regulatory subunit 3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A
:  FLFL1 FLJ20707 KIAA2010 MSTP033 PP4R3 PP4R3A protein phosphatase 4, regulatory subunit 3A SMEK homolog 1 SMEK homolog 1, suppressor of mek1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) SMEK1 smk1 smk-1
Product
Specifications
Ordering Information
Human
IP
Between 600 and 650
$339
$99
Human
WB, IP, IHC, IF
Between 770 and C-term
$339
$229
$99
Human
WB, IP, IHC, IF
Includes: 1 each of A300-839A and A300-840A
$472
Includes: 1 each of A300-839A and A300-840A
Human, Mouse
IHC, IF
Between 770 and C-term
$360
$99