PARN Antibody

Poly(A)-specific ribonuclease (PARN) is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. PARN prefers poly(A) as the substrate, hence, it efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. PARN is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons [taken from NCBI Entrez Gene (Gene ID: 5073)].
PARN
poly(A)-specific ribonuclease
Poly(A)-specific ribonuclease PARN
:  DAN deadenylating nuclease deadenylation nuclease DKCB6 PFBMFT4 poly(A)-specific ribonuclease (deadenylation nuclease) polyadenylate-specific ribonuclease
Product
Specifications
Ordering Information
Human
WB, IP
Between 539 and 589
$339
$229
$99
Human, Mouse
WB, IP, IHC
Between 589 and 639
$339
$229
$99
Human, Mouse
WB, IP, IHC
Includes: 1 each of A303-561A and A303-562A
$472
Includes: 1 each of A303-561A and A303-562A